What is the ASDproteinpattern autism blood test?
The iDiagnostix Autism Spectrum Disorder blood test (ASDproteinpattern) is a new diagnostic test to help children and families affected by ASD get an earlier diagnosis. It is a screening test that greatly increases the identification of ASD in children and decreases the risk that children with ASD are overlooked.
Our test measures modifications of proteins in the blood reporting on metabolic disturbances in the brain of children affected by ASD. These were found in our Discovery study and then confirmed in our independent Validation study. The results of our autism test are available in one week. A positive test greatly increases the likelihood that a child has autism, and a negative test greatly increases the likelihood that a child does not have autism. It is a screening test and, as per Federal Drug administration (FDA) guidelines for all autism tests, positive outcomes are to be confirmed by a child development expert – child psychologist or psychiatrist. Our test greatly improves the effectiveness of expert referral – ensuring children referred are highly likely to have autism.
A test for earlier ASD diagnosis with easier access and higher confidence
Earlier diagnosis of ASD and intervention can help children improve and often achieve remission from unpleasant symptoms. The average age of diagnosis in the United States and Europe/UK is more than 4 years. Our ASDproteinpattern blood test can help children from 18 months old receive an earlier diagnosis. Children with ASD can then begin treatment sooner.
The ASDproteinpattern is clinical chemistry test with truly objective outcomes. As such, you can have high confidence in the outcome wherever it is performed and access to it may be made widely available.
What is the ASDproteinpattern autism blood test?
Our test measures modifications on proteins in plasma – mainly on a protein called albumin. Albumin is present in fluid of the brain, cerebrospinal fluid, where it receives modification related to metabolic status of the brain. Albumin of cerebrospinal fluid is released into blood plasma and thereby these protein modifications are detected in a simple blood sample. Modifications report on many things but the ones related to autism indicate changed glucose metabolism, increased oxidation of lipids or lipid peroxidation, protein misfolding and neuroplasticity. The modifications accumulate on albumin over 3 to 4 weeks and so the overall level is not influenced by temporary fluctuations – as would be the case if metabolites were measured directly. These four kinds of modification help us to diagnose the presence or absence of autism.
When autism is present, the levels of two additional modifications are linked to the severity of autism. This provides, for the first time, a blood test for autism severity.
These screening test for autism diagnosis and the blood test for autism severity are currently highly sought after. iDiagnostix is stepping forward to provide this vital support to family and carers of those suspected to have autism, physicians and child development experts.
These screening test for autism diagnosis and the blood test for autism severity are currently highly sought after. iDiagnostix is stepping forward to provide this vital support to family and carers of those suspected to have autism, physicians and child development experts.
Highly accurate blood test able to identify ASD in all children
The ASDproteinpattern blood test for autism detects protein modifications related to metabolic changes in the brain common to all children across the spectrum of autism. So, there is always a response: it has a 100% response rate. The test can even distinguish between children with and without autism of the same family where other tests may fail. The accuracy is 83 – 88% – higher than the threshold of 80% recommended by the American Psychiatric Association. Indeed, it is the first test to meet this level of accuracy in both the Discovery study and the Validation study. Our Validation phase study had added surety of outcome as it was an independent, multi-center international study involving a large number of children.