The primary aim of our research in autism is to support clinicians in making the process of diagnosis quicker and more accurate.
The benefit of early diagnosis will allow those who have autism to get the support and care that they need at the earliest opportunity. Early intensive intervention leads to reduction in the adverse impact of the condition, improves the quality of the lives of all those affected (including family members) and saves billions in both direct medical costs, and associated economic losses.
We received media attention for our work in developing a blood test which may help in the diagnosis of autism. In this test we compared blood samples between those with autism and those without to see if there was any difference in certain proteins (including some known to be associated with autism)
Autism blood discovery promises earlier tests and treatmentRead more at telegraph.co.uk
Study Reveals First Signs of AutismRead more at thepeninsulaqatar.com
Our results suggested that there is a difference in the concentration of certain proteins between the two groups, which may provide a potential biomarker for autism. The advantage in studying the endogenous damage to the proteome as biomarkers in combination with the artificial intelligence is that:
- Glycated, oxidised and nitrated (damaged) amino acids do not re-incorporate into proteins and hence changes more readily occur than for normal metabolites
- They are directly linked to mechanisms of chronic disorders – thereby often studying a risk factor or cause of disorder rather than symptom of it
- They are often also risk predictors – applicable for early-stage diagnosis, progression and therapeutic monitoring of condition
In order to determine whether or not our findings can be used formally as a blood tests requires a much larger study. Our aims are ambitious but we believe that our work breaks new ground in understanding of a condition which holds significance for so many.
For a visual overview of the research concepts behind ASD Protein Pattern™, see our short slide deck.
Header image by Illinois Springfield and used under CC BY-NC-ND 2.0.